Study: Cardamom Should Be Part Of The Diet Of Every Diabetic Patient
Cardamom has a widely known antioxidant and anti-cancer activity. Recently, a randomized control trial (RCT), which was published in BMC Complementary and Alternative Medicine, has validated its anti-diabetic properties. The study has the aim of looking at the effects of green cardamom on blood sugar levels, oxidative stress status, and cholesterol levels in people with Type 2 diabetes.
In this study, the researchers wrote that:
“To determine the mechanism of cardamom effect on blood glucose and lipid levels, blood irisin, and SIRT1 [Sirtuin1] will be assessed.”
SIRT1 plays an important role in glucose metabolism and decrease cases of insulin resistance. Meanwhile, irisin is known to be an enzyme which can improve insulin sensitivity and glucose metabolism, one of the things impaired by Type 2 diabetes. Previous studies revealed that cardamom is activated during exercise in both mouse and human studies, thus labeling it as the exercise hormone. During that time, researchers considered irisin as a potential candidate for interventions for obesity, weight loss, and diabetes.
The RCT involved 80 patients whom are either obese or overweight and have Type 2 diabetes. They were randomly assigned into two groups: one is provided with a dosage of three grams of green cardamom supplement a day, while the other is to receive a placebo. The test, which will run for 30, will measure different biological and physical markers in order for the researchers to determine whether supplementing with green cardamom can improve these markers in people who have the condition.
The researchers added that:
“The selection of patients with T2DM [Type 2 diabetes mellitus] is the main strength of the present study. To the best of our knowledge, this is the first randomized controlled trial that will determine the effect of cardamom on glycemic status, lipid profile, oxidative stress biomarkers, SIRT1 and irisin in T2DM.”
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